Tips to Improve the slow performance of QC/ client load faster

Here is some good tips found in KM862096/KM450424, hope this will help you...
Steps need to be taken to improve the slow performance of Quality Center:
1. Compression
The Client Server compression mechanism that was originally developed for QC10.0 and QC 9.2 is applied. If working in a LAN environment, these improvements will probably not have a major effect. That said, improved performance will still be observed.

2. Using QCExplorer and a desktop installation
If QCExplorer is installed, then it will skip the file download phase and will improve login times.

3. Avoiding the use of a blank filter upon login to the Defects module
When the user enters the defects module, the system runs the last filter to retrieve the list of defects. If there is an empty filter, the returned list of defects can be very large. That is, the users should not logout with an empty filter. In these cases, a simple filter of "assigned to = " may improve login times.

4. Using the same machines for subsequent logins
Since QC client uses a local cache for all kinds of settings, subsequent log-ins from the same machine should be a lot faster than the first login from that machine.

5. Leaving QC Open
If QC is left running, the slow login is possibly avoided.


Login performance is slow with Quality Center client startup

Cause
Network latency in the system environment
QC files are being checked by anti-virus software during cold startup of Internet Explorer
Version and signature checks are being performed on all QC files

Fix
Tips to make Quality Center client load faster:
Reduce network latency to less than 200 ms
Do not close IE window after logging out from QC
Put QC files in the exception list of the antivirus software
For example: Put all the files in the following folder and sub folders in the exception list of the antivirus software: C:\Program Files\Common Files\Mercury Interactive\Quality Center.

NOTE: QC must be at patch 10 or above to see the loading progress.